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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPTOR
All Species:
31.21
Human Site:
S738
Identified Species:
62.42
UniProt:
Q8N122
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N122
NP_065812.1
1335
149038
S738
T
A
R
S
L
N
K
S
L
Q
N
L
S
L
T
Chimpanzee
Pan troglodytes
XP_001161716
1335
149161
S738
T
A
R
S
L
N
K
S
L
Q
N
L
S
L
T
Rhesus Macaque
Macaca mulatta
XP_001110471
1335
148870
S738
T
A
R
S
L
N
K
S
L
Q
N
L
S
L
T
Dog
Lupus familis
XP_850487
1335
149172
S738
T
A
R
S
L
N
K
S
L
Q
N
L
S
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q0
1335
149453
S738
T
A
R
N
L
N
K
S
L
Q
N
L
S
L
T
Rat
Rattus norvegicus
NP_001127971
1335
149475
S738
T
A
R
N
L
N
K
S
L
Q
N
L
S
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426232
1335
149895
S738
T
A
R
N
L
N
K
S
L
Q
N
L
S
L
N
Frog
Xenopus laevis
NP_001088177
1334
149513
S736
T
P
R
N
L
N
K
S
L
Q
N
L
S
L
S
Zebra Danio
Brachydanio rerio
XP_001919288
1332
149175
K738
T
T
A
R
T
L
N
K
S
L
Q
N
L
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624060
1279
144157
L691
E
E
N
S
R
K
D
L
V
V
E
T
L
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002323654
1366
149968
P763
I
N
P
N
Q
H
V
P
H
A
S
I
V
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38873
1557
177591
L894
K
R
Q
E
I
G
N
L
I
S
I
L
P
L
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.8
95.9
N.A.
96.5
96.7
N.A.
N.A.
95
90.5
87.9
N.A.
N.A.
55.5
N.A.
N.A.
Protein Similarity:
100
99.5
99.1
98.3
N.A.
98.4
98.5
N.A.
N.A.
97.6
95.9
94.6
N.A.
N.A.
70.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
6.6
N.A.
N.A.
13.3
N.A.
N.A.
Percent
Protein Identity:
40.8
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
58.2
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
9
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
9
0
9
9
0
0
9
% I
% Lys:
9
0
0
0
0
9
67
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
67
9
0
17
67
9
0
75
17
75
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
42
0
67
17
0
0
0
67
9
0
9
9
% N
% Pro:
0
9
9
0
0
0
0
9
0
0
0
0
9
0
9
% P
% Gln:
0
0
9
0
9
0
0
0
0
67
9
0
0
0
0
% Q
% Arg:
0
9
67
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
42
0
0
0
67
9
9
9
0
67
17
17
% S
% Thr:
75
9
0
0
9
0
0
0
0
0
0
9
0
0
50
% T
% Val:
0
0
0
0
0
0
9
0
9
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _